CBD oil has several pharmacological purposes in people of various ages, particularly for addressing sicknesses among seniors. Learn more about CBD oil for seniors below, including the absorption and administration and the factors to consider when purchasing CBD oil.
Seniors are among the most susceptible individuals. They are vulnerable to getting injured or sick while taking a long to recover. Aging is a great opportunity to re-evaluate and appreciate life through wisdom gathered over the years. Thanks to modern scientific research, seniors can select various natural remedies to address health strains resulting from old age. Recently, most people have been interested in cannabidiol (CBD) due to its related wellness products and oils for unique health benefits. CBD oil has several pharmacological purposes in people of various ages, particularly for addressing sicknesses among seniors. Need more information about CBD oil in seniors? Keep reading this blog.
Delta-9 tetrahydrocannabinol (THC) and cannabidiol (CBD) constitute the numerous cannabinoid components or compounds of the cannabis sativa herb. CBD is non-psychoactive, while THC contains psychoactive properties, including psychosis and euphoria. Hemp and marijuana are the common cannabis sativa varieties. CBD can be sourced from either hemp (containing 0.3% or below THC concentration) or marijuana (contains beyond 15 percent THC). In addition, cannabidiol might be derived from hybrid plants and cannabis indica, containing higher cannabidiol concentrations than THC.
Recently, Brzozowska et al. (2016) deduced that CBD interacts with many chemicals, proteins, and receptors in the brain. It moderates various responses, emotions, and cycles. The human body synthesizes its cannabinoids within the endocannabinoid system (ECS). This system normalizes infinite processes in the body, including stress, digestion, immune function, reproduction, appetite, pain perception, and mood. According to Di Marzo & Piscitelli (2015), CBD coordinates with different cannabinoids to promote the endocannabinoid system. The system comprises three components such as receptors, endocannabinoids, and enzymes. The enzymes serve an important function in metabolizing endocannabinoids. The main receptors consist of CB2 and CB1. CB2 receptors reside in the human peripheral system, prompting inflammation and pain. CB1 receptors are present in the central nervous system and regulate mood, appetite, pain, movement, memory, and coordination. After enzymes digest cannabinoids, the endocannabinoids start influencing receptors. Baswan et al. (2020) showed that cannabidiol cannot bind ECS receptors directly but impacts them in multiple means. Stimulating CB2 and CB1 receptors generate many therapeutic benefits that users reap from cannabidiol oil. Similarly, some studies established that cannabidiol impacts other non-cannabinoid receptors. For example, it regulates the 5ht serotonin receptor that alleviates psychotic disorders. Besides, CBD stimulates the TRPV1 receptor, which moderates inflammation and pain. Some suggested cannabidiol functioning mechanisms comprise agonist action at temporary receptor potential vallinoid 1, adenosine A2A receptors, G-protein coupled receptor 55, and serotonin 1A. These mechanisms explain certain possible anti-inflammatory, antiepileptic, analgesic, anxiolytic cannabidiol effects. Some US states have legalized cannabis for medicinal purposes, while others have recreational. CBD has not undergone Food and Drug Administration (FDA) certification. However, Epidiolex, a CBD-based drug, is approved by FDA to treat particular ailments like seizures. The law banned dietary or food supplement marketing where CBD products were included. However, various CBD products are available in many retail shops.
Cannabidiol absorption is determined by product formulation. Cherniakov et al. (2017) showed that cannabidiol administered orally is absorbed poorly, with between 13-19 % bioavailability. Biologically, cannabidiol's bioavailability is delayed by first-pass processing. Poor bioavailability is evaded by utilizing alternative formulations. Important delivery mechanisms emerge to elevate cannabidiol's oral bioavailability. CBD absorption might be affected by food consumption. Taking CBD oil while full lowers bioavailability, but on an empty stomach increases the bioavailability rate. Interestingly, CBD oil's positive effects remain longer than with other formulations.
Some medical providers claim that cannabidiol is suitable for seniors. However, others suggest that the evidence is insufficient but regard them as probably safe. There is no documented research indicating the exact CBD dose. This implies that CBD consumption dose varies with consumers. However, excessive cannabidiol ingestion in seniors might cause elevated liver function, diarrhea, decreased appetite, and sleepiness. Other potential side effects are orthostatic hypotension, dry mouth, and lightheadedness. Scientists have established that adverse side effects have a strong link with dosage. Consumers should understand their accurate regimen and dose to acquire the anticipated effects. Manufacturers recommend CBD beginners to start with a low dosage and increase with time. Individuals taking other medications should consult their medical providers before using CBD oil. Notably, seniors are prohibited from substituting their prescribed medications with cannabidiol products.
Cannabidiol products can be provided in three formulations: full-spectrum cannabidiol includes all compounds present in cannabis herbs like terpenes, flavonoids, THC, and other cannabinoids. This extract can cause have intoxicating effects depending on tetrahydrocannabinol concentration. Broad-spectrum cannabidiol is loaded with all cannabis herb compounds except THC. In contrast, Isolate cannabidiol is the purest CBD extract since it contains cannabidiol contents exclusively. Fortunately, isolating cannabidiol does not expose you to allergic reactions risks present in other oil compounds. Seniors using only broad-spectrum or isolated CBD products pass drug screening. However, full and broad-spectrum CBD products benefit consumers with an entourage effect. CBD enthusiasts reported positive health impacts, including improved muscle spasms, nausea, appetite stimulation, pain, and sleep.
Despite many CBD health benefits, taking illegitimate products have negative effects. Therefore, consider the following:
Old age is also accompanied by its predicaments. Many health issues are common among seniors. Scientists established that CBD is a safe, natural substitute for pharmaceutical prescriptions when addressing aging problems. Several seniors have reported positive effects, including muscle spasms, nausea, appetite stimulation, pain, and sleep improvement after taking CBD oil. Beginners are required to start with low amounts and increase with time. Also, inform your medical provider upon cannabidiol usage for guidance. Seniors who want to avoid intoxicating effects should take isolated CBD. Furthermore, all CBD oils should be purchased from a reputable brand that provides a COA report for transparency and safety.
Baswan, S. M., Klosner, A. E., Glynn, K., Rajgopal, A., Malik, K., Yim, S., & Stern, N. (2020). Therapeutic Potential Of Cannabidiol (CBD) For Skin Health And Disorders. Clinical, Cosmetic And Investigational Dermatology, 13, 927.
Brzozowska, N., Li, K. M., Wang, X. S., Booth, J., Stuart, J., Mcgregor, I. S., & Arnold, J. C. (2016). ABC Transporters P-Gp And Bcrp Do Not Limit The Brain Uptake Of The Novel Antipsychotic And Anticonvulsant Drug Cannabidiol In Mice. Peerj, 4, E2081.
Cherniakov, I., Izgelov, D., Domb, A. J., & Hoffman, A. (2017). The Effect Of Pro Nanolipospheres (PNL) Formulation Containing Natural Absorption Enhancers On The Oral Bioavailability Of Delta-9-Tetrahydrocannabinol (THC) And Cannabidiol (CBD) In A Rat Model. European Journal Of Pharmaceutical Sciences, 109, 21-30.
Di Marzo, V., & Piscitelli, F. (2015). The Endocannabinoid System And Its Modulation By Phytocannabinoids. Neurotherapeutics, 12(4), 692-698.